Laboratorio de Biomateriales y Bioingeniería
CITSAM Centro de Investigación Traslacional San Alberto Magno
UCV Universidad Católica de Valencia San Vicente Mártir
Publicaciones seleccionadas
Autoimmune response after SARS-CoV-2 infection and SARS-CoV-2 vaccines, Autoimmunity Reviews 23, 3, 103508, 2024
Biocompatible Ti3Au–Ag/Cu thin film coatings with enhanced mechanical and antimicrobial functionality, Biomaterials Research 27, 93 (2023)
In vivo and in vitro Biocompatible Alginate Film Crosslinked with Ca2+ and Co2+ Manifests Antiviral, Antibacterial and Anticancer Activity, European Polymer Journal 197, 112377 (2023)
Multi-functional bioactive silver- and copper-doped diamond-like carbon coatings for medical implants. Acta Biomaterialia 2023; 167,54-68
Antimicrobial Lipstick: Bio-based Composition against Viruses, Bacteria and Fungi. ACS Applied Materials & Interfaces 2022, 14, 51, 56658–56665
Engineering 3D Printed Bioactive Polylactic Acid Alginate Composite Scaffolds with Antibacterial and In Vivo Osteoinductive Capacity. ACS Applied Materials & Interfaces 2022, 14, 48, 53593–53602
Engineering alginate hydrogel films with poly(3-hydroxybutyrate-co-3-valerate) and graphene nanoplatelets: Enhancement of antiviral activity, cell adhesion and electroactive properties. International Journal of Biological Macromolecules, 219, 694-708
Carbon-Based Nanomaterials: Promising Antiviral Agents to Combat COVID-19 in the Microbial Resistant Era. ACS Nano 2021, 15, 5, 8069–8086
Protective Face Masks: Current Status and Future Trends. ACS Applied Materials & Interfaces 2021, https://doi.org/10.1021/acsami.1c12227
Fused Deposition Modelling: Current Status, Methodology, Applications and Future Prospects. Additive Manufacturing 2021, 47, 102378
Fourth Generation Glucose Sensors Composed of Copper Nanostructures for Diabetes Management: A Critical Review. Bioengineering Translational Medicine 2021
The mechanism behind flaring/triggering of autoimmunity disorders associated with COVID-19. Autoimmunity reviews 2021.
Graphene Oxide Nanosheets versus Carbon Nanofibers: Enhancement of Physical and Biological Properties of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Films for Biomedical Applications, International Journal of Biological Macromolecules 143, 1000-1008, 2020.
Physical and Biological Properties of Alginate/Carbon Nanofibers Hydrogel Films, International Journal of Biological Macromolecules 151, 499-507, 2020.
A spatio-temporal analysis for exploring the effect of temperature on COVID-19 early evolution in Spain, Science of the Total Environment 728, 138811, 2020.
Publicaciones por año
2024
Metabolites as a Potential Therapeutic Intervention in Managing Viral Diseases: Insights from In Silico and Pre-clinical Studies. Pharmaceuticals 2024, 17(3), 328
Autoimmune response after SARS-CoV-2 infection and SARS-CoV-2 vaccines, Autoimmunity Reviews 23, 3, 103508, 2024
Non-coding RNAs as Key Regulators of the Notch Signaling Pathway in Glioblastoma: Diagnostic, Prognostic, and Therapeutic Targets, CNS & Neurological Disorders - Drug Targets (IF: 3.2) 2024
SARS-CoV-2 NSP14 governs mutational instability and assists in making new SARS-CoV-2 variants, Computers in Biology and Medicine 170, 107899
2023
Biocompatible Ti3Au–Ag/Cu thin film coatings with enhanced mechanical and antimicrobial functionality, Biomaterials Research 27, 93 (2023)
Carbon nanotube-wastewater treatment nexus: Where are we heading to?. Environmental Research 2023, 238, 117088
Biocompatible Alginate Hydrogel Film Containing Acetic Acid Manifests Broad-Spectrum Antiviral and Anticancer Activities. Biomedicines 2023, 11(9), 2549
Synthesis and characterization of nanobiochar from rice husk biochar for the removal of safranin and malachite green from water, Environmental Research 2023, 238, 116909
In vivo and in vitro Biocompatible Alginate Film Crosslinked with Ca2+ and Co2+ Manifests Antiviral, Antibacterial and Anticancer Activity, European Polymer Journal 197, 112377 (2023)
Tiger nut milk’s antiviral properties against enveloped and non-enveloped viruses: effect of concentration and adding sugar, International Journal of Molecular Sciences 2023, 24(15), 12018
Biocompatible chitosan films containing acetic acid manifested potent antiviral activity against enveloped and non-enveloped viruses, International Journal of Molecular Sciences 2023, 24(15), 12028
Study of biological properties of gold nanoparticles: low toxicity, no proliferative activity, no ability to induce cell gene expression and no antiviral activity, Chemico-Biological Interactions 2023, 382, 110646
Development and validation of Ran as a prognostic marker in stage I and stage II primary breast cancer. Life Sciences 2023, 329, 121964
Multi-functional bioactive silver- and copper-doped diamond-like carbon coatings for medical implants. Acta Biomaterialia 2023; 167,54-68
Biocompatible alginate film crosslinked with Ca2+ and Zn2+ possesses antibacterial, antiviral and anticancer activities, ACS Omega 2023; 8, 27, 24396–24405
Photonic nanoparticles: emerging theranostics in cancer treatment. Therapeutic Delivery 14 (4), 2023
Applications of Trimetallic Nanomaterials as Non-Enzymatic Glucose Sensors, Drug Development and Industrial Pharmacy 2023, 49 (6)
Alcoholic and non‑alcoholic rosé wines made with Saccharomyces cerevisiae var. boulardii probiotic yeast, Archives of Microbiology (2023) 205:201
Role of Mammalian Target of Rapamycin (mTOR) Signalling in Oncogenesis, Life Sciences (IF:6.78) 323, 121662, 2023
Ran GTPase and its Importance in Cellular Signaling and Malignant Phenotype. International Journal of Molecular Sciences 2023, 24(4), 3065;
Nanomaterials and Their Impact on the Immune System, International journal of Molecular Sciences 2023, 24(3), 2008
Cellular and Molecular Basis of Therapeutic Approaches to Breast Cancer Cellular Signalling. Cellular Signalling 2023, 101, 110492.
COVID-19 Signalome: Pathways for SARS-CoV-2 Infection and Impact on COVID-19 Associated Comorbidity. Cellular Signalling 101 (2023) 110495.
2022
Antimicrobial Lipstick: Bio-based Composition against Viruses, Bacteria and Fungi. ACS Applied Materials & Interfaces 2022, 14, 51, 56658–56665
Engineering 3D Printed Bioactive Polylactic Acid Alginate Composite Scaffolds with Antibacterial and In Vivo Osteoinductive Capacity. ACS Applied Materials & Interfaces 2022, 14, 48, 53593–53602
Cellular and Molecular Basis of Therapeutic Approaches to Breast Cancer Cellular Signalling. Cellular Signalling 2023, 101, 110492
Matrix metalloproteinase 2 is a target of the RAN-GTP pathway and mediates migration, invasion and metastasis in human breast cancer. Life Sciences 2022, 310, 121046
Non-Uniform Aspects of SARS-CoV-2 Intraspecies Evolution Reopen Questions on Its Origin, International Journal of Biological Macromolecules 2022, 222, 972-993
Advances in Nanomaterial-Based Immunosensors for Prostate Cancer Screening. Biomedicine & Pharmacotherapy 2022, 155, 113649
Engineering alginate hydrogel films with poly(3-hydroxybutyrate-co-3-valerate) and graphene nanoplatelets: Enhancement of antiviral activity, cell adhesion and electroactive properties. International Journal of Biological Macromolecules, 219, 694-708
Frontiers in Antimicrobial Materials. International Journal of Molecular Sciences 2022, 23(14), 8047
Protein-based nanomaterials: a new tool for targeted drug delivery. Therapeutic Delivery 13(6)
2D materials, synthesis, characterization and toxicity: A critical review. Chemico-Biological Interactions 365, 110081, 2022
Application of nanotechnology to herbal antioxidants as improved phytomedicine: An expanding horizon. Biomedicine & Pharmacotherapy, 153, 113413, 2022
Nanomedicine: Protein-Based Drug Delivery Nanomedicine Platforms: Recent Developments. Pharmaceutical nanotechnology 2022.
Therapeutic Potential of Cannabinoids on Tumor Microenvironment: A Molecular Switch in Neoplasia Transformation. Integrative Cancer Therapies 2022
Association of COVID-19 with congenital and genetic disorders: a comprehensive review. Viruses 2022, 14(5), 910
Biomedical applications of three-dimensional bioprinted craniofacial tissue engineering. Bioengineering & Translational Medicine, e10333 .
Exosomal mediated signal transduction through artificial microRNA (amiRNA): a potential target for inhibition of SARS-CoV-2. Cellular Signalling 95, 110334.
Biocompatible Films of Calcium Alginate Inactivate Enveloped Viruses Such as SARS-CoV-2. Polymers 14(7), 1483
Electroactive calcium-alginate/polycaprolactone/reduced graphene oxide nanohybrid hydrogels for skeletal muscle tissue engineering. Colloids and Surfaces B: Biointerfaces 214 (2022) 112455
Recent Advances in Metal-based Antimicrobial Coatings for High-touch Surfaces. Int. J. Mol. Sci. (2022) 23(3), 1162
Recent Advances in Anticancer Activity of Novel Plant Extracts and Compounds from Curcuma longa in Hepatocellular Carcinoma. J Gastrointest Canc (2022). https://doi.org/10.1007/s12029-022-00809-z
Gene Therapy for Neuropsychiatric Disorders: Potential Targets and Tools. CNS & Neurological Disorders - Drug Targets, 2022
The Importance of Accessory Protein Variants in the Pathogenicity of SARS-CoV-2. Archives of Biochemistry and Biophysics 717,109124, 2022
Graphene Nanoplatelets: In Vivo and In Vitro Toxicity, Cell Proliferative Activity, and Cell Gene Expression. Applied Sciences 12(2), 720
Emergence of unique SARS-CoV-2 ORF10 variants and their impact on protein structure and function. International Journal of Biological Macromolecules 194,128-143, 2022
Periodically aperiodic pattern of SARS-CoV-2 mutations underpins the uncertainty of its origin and evolution. Environmental Research 204B, 112092, 2022
On the association between COVID-19 vaccination levels and incidence and lethality rates at a regional scale in Spain. Stochastic Environmental Research and Risk Assessment 2022
A city-level analysis of PM2.5 pollution, climate and COVID-19 early spread in Spain. Journal of Environmental Health Science and Engineering 2022
2021
Protective Face Masks: Current Status and Future Trends. ACS Applied Materials & Interfaces 2021, https://doi.org/10.1021/acsami.1c12227
Carbon-Based Nanomaterials: Promising Antiviral Agents to Combat COVID-19 in the Microbial Resistant Era. ACS Nano 2021, 15, 5, 8069–8086
Fused Deposition Modelling: Current Status, Methodology, Applications and Future Prospects. Additive Manufacturing 2021, 47, 102378
The mechanism behind flaring/triggering of autoimmunity disorders associated with COVID-19. Autoimmunity reviews 2021.
Fourth Generation Glucose Sensors Composed of Copper Nanostructures for Diabetes Management: A Critical Review. Bioengineering Translational Medicine 2021
Antimicrobial face shield: next generation of facial protective equipment against SARS-CoV-2 and multidrug-resistant bacteria. International Journal of Molecular Sciences 2021, 22(17), 9518
Carbon Nanofibers versus Silver Nanoparticles: Time-dependent Cytotoxicity, Proliferation, and Gene Expression. Biomedicines 2021, 9(9), 1155
Potential Molecular Mechanisms of Rare Anti-Tumor Immune Response by SARS-CoV-2 in Isolated Cases of Lymphomas. Viruses 2021, 13(10), 1927
Clinical utility of novel biosensing platform: Diagnosis of coronavirus SARS-CoV-2 at point of care. Materials letters 304 (2021) 130612
Overview of Key Molecular and Pharmacological Targets for Diabetes and Associated Diseases. Life Sciences 2021, 278, 119632
Prosthetic Meshes for Hernia Repair: State of Art, Classification, Biomaterials, Antimicrobial Approaches, and Fabrication Methods. Journal of Biomedical Material Research A, 2021;
Predicting COVID-19—Comorbidity Pathway Crosstalk-Based Targets and Drugs: Towards Personalized COVID-19 Management. Biomedicines 2021, 9(5), 556
A Unique View of SARS-COV-2 through the Lens of ORF8 Protein. Computers in Medicine and Biology, 2021,
Notable sequence homology of the ORF10 protein introspects the architecture of SARS-COV-2. International Journal of Biological Macromolecules 181, 801-809, 2021
Enhancement of Antimicrobial Activity of Alginate Films with a Low Amount of Carbon Nanofibers (0.1% w/w). Applied Science 11(5), 2311, 2021
Implications derived from S-protein variants of SARS-CoV-2 from six continents. International Journal of Biological Macromolecules 191, 934-955 , 2021
Exploiting the Metabolism of the Gut Microbiome as a Vehicle for Targeted Drug Delivery to the Colon. Pharmaceuticals 14(12), 1211, 2021.
3D Printed Cobalt-Chromium-Molybdenum Porous Superalloy with Superior Antiviral Activity. International Journal of Molecular Sciences 22(23), 12721, 2021.
Non-Woven Infection Prevention Fabrics Coated with Biobased Cranberry Extracts Inactivate Enveloped Viruses Such as SARS-CoV-2 and Multidrug-Resistant Bacteria. International Journal of Molecular Sciences 22(23), 12719, 2021.
Green Composites Films with Antibacterial Properties. In: Thomas S., Balakrishnan P. (eds) Green Composites. Materials Horizons: From Nature to Nanomaterials. Springer, Singapore, pp 485-506, 2021.
2020
STRUCTURAL SNAPSHOT: The Structural Basis of Accelerated Host Cell Entry by SARS‐CoV‐2. The FEBS Journal, 2020.
Injectable Gel Form of a Decellularized Bladder Induces Adipose-Derived Stem Cell Differentiation into Smooth Muscle Cells In Vitro, International Journal of Molecular Sciences 21, 8608, 2020
Graphene Oxide Nanosheets versus Carbon Nanofibers: Enhancement of Physical and Biological Properties of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Films for Biomedical Applications, International Journal of Biological Macromolecules 143, 1000-1008, 2020.
Physical and Biological Properties of Alginate/Carbon Nanofibers Hydrogel Films, International Journal of Biological Macromolecules 151, 499-507, 2020.
A spatio-temporal analysis for exploring the effect of temperature on COVID-19 early evolution in Spain, Science of the Total Environment 728, 138811, 2020.
The effect of climate on the spread of the COVID-19 pandemic: a review of findings and statistical methods, Progress in Physical Geography, 1-14, 2020.
Changes in air pollution during COVID-19 lockdown in Spain: a multi-city study, Journal of Environmental Sciences 101, 16-26, 2020.
Acrylic-Based Hydrogels as Advanced Biomaterials, In A. Serrano-Aroca and S. Deb (Eds.), Acrylate polymers for advanced applications, IntechOpen, ISBN 978-1-78985-183-0 (2020)
Acrylic-Based Materials for Biomedical and Bioengineering Applications. In A. Serrano-Aroca and S. Deb (Eds.), Acrylate polymers for advanced applications, IntechOpen, ISBN 978-1-78985-183-0 (2020)
2019
Carbon Nanomaterials and LED Irradiation as Antibacterial Strategies against Gram-positive Multidrug-resistant Pathogens, International Journal of Molecular Science 2019, 20(14), 3603.
Saccharomyces Cerevisiae Var. Boulardii: Valuable Probiotic Starter for Craft Beer Production, Applied Science 2019, 9(16), 3250.
Human Adipose-derived Mesenchymal Stem Cells Accelerate Decellularized Neobladder Regeneration, Regenerative Biomaterials, rbz049.
2018
Poly(2-hydroxyethyl acrylate) hydrogels reinforced with graphene oxide: remarkable improvement of water diffusion and mechanical properties. Journal of Applied Polymer Science, 135, 46158.
Green synthetic routes to alginate-graphene oxide composite hydrogels with enhanced physical properties for bioengineering applications, European Polymer Journal, 103, 198-206 (2018).
Bioengineering approaches for bladder regeneration, International Journal of Molecular Sciences 19, 1796.
Antimicrobial Characterization of Advanced Materials for Bioengineering Applications, J. Vis. Exp. (138), e57710.
Enhancement of Hydrogel’s properties for Biomedical Applications: Latest Achievements. In S. Haider and A. Haider (Eds.), Hydrogels, InTech, pp 91-120 (2018)
2017
Dynamic mechanical analysis and water vapour sorption of highly porous poly(methyl methacrylate). Polymer 125:58-65. (2017)
Enhancement of water diffusion and compression performance of crosslinked alginate films with a minuscule amount of graphene oxide. Scientific Reports 7:11684 (2017)
Synthesis of irregular graphene oxide tubes using green chemistry and their potential use as reinforcement materials for biomedical applications. PloS ONE 12(9):e0185235. (2017)
Latest Improvements of Acrylic-Based Polymer Properties for Biomedical Applications. In Boreddy S.R. Reddy (Ed.), Acrylic polymers in healthcare, InTech, ISBN 978-953-51-3594-4, Print ISBN 978-953-51-3593-7, pp 75-98 (2017)
Patentes y Modelos de utilidad
1. Biomaterial Biodegradable (Patente).
P202030999. 02 Oct 2020
P202030999. 02 Oct 2020
2. Andamio biodegradable antimicrobiano para ingeniería tisular ósea y procedimiento para su obtención (Patente).
P202031200. 02 Dic 2020.
P202031200. 02 Dic 2020.
3. Elemento de protección facial frente a riesgos de exposición de agentes biológicos infecciosos (Modelo de utilidad).
U202130782. 15 Abril 2021.
4. Síntesis de nuevos materiales hidrófilos biodegradables de origen natural (Patente). P202230138. 21 Feb 2022.
5. Malla quirúrgica mejorada para reparación de hernias (Patente). EP22383246 and PCT/EP2023/085942, 2024.